Can Fertility Treatment Cause Cancer?

Published:
July 31, 2025

If you’ve ever gone down a late night internet rabbit hole researching fertility treatments, chances are you’ve stumbled upon a headline that made your stomach drop: Can fertility treatment cause cancer? 

It’s a scary question, and understandably so. When you’re already juggling hormones, hopes, and financial stress, the idea that fertility meds might pose long term health risks is enough to make anyone second guess their treatment plan.

Let’s break it down. What’s true? What’s hype? And how should you approach your fertility journey with confidence?

The Concern: Hormones and Cancer Risk

Fertility treatments often involve medications that stimulate ovulation, such as Clomiphene Citrate (Clomid) or injectable gonadotropins. These drugs encourage your ovaries to produce multiple eggs, increasing your chances of pregnancy. 

However, they manipulate hormone levels - especially estrogen - it’s natural to wonder if they could also increase your risk of hormone related cancers like breast or ovarian cancer.

What Research Tells Us

So, can fertility treatment cause cancer? Here’s where science comes in clutch.

  • Multiple large scale studies have found no consistent link between fertility medications and breast or ovarian cancer in women without other risk factors.

  • A 2016 review published in Fertility and Sterility concluded that Clomid and gonadotropins do not significantly increase cancer risk when used under medical supervision.

  • Some older studies raised concerns, particularly in women who used fertility meds for many cycles or never became pregnant, but newer, more comprehensive data has largely put those fears to rest.

Can Fertility Treatment Cause Cancer?

This question has been studied extensively. While no treatment is 100% risk free, the general medical consensus is that fertility medications do not pose a significant cancer risk for most women - especially when used in moderation and under expert care.

That said, there are exceptions. If you have a family history of breast, ovarian, or uterine cancer, or have genetic mutations like BRCA1/2, it’s crucial to have an open conversation with your provider. Your fertility plan may need to be adjusted or monitored more closely.

Other Factors to Consider

Keep in mind that infertility itself - especially when linked to endometriosis, PCOS, or unexplained anovulation - has been associated with a slightly higher risk of certain cancers. So in some cases, it’s not the fertility treatment but the underlying condition that may affect long term health.

This is where a trusted fertility specialist makes all the difference. With proper screening, a personalized treatment plan, and regular follow ups, your health remains the priority every step of the way.

Be Informed, Not Alarmed

The internet is filled with anecdotal horror stories and outdated studies, but the most current research continues to support the safety of fertility medications for the vast majority of patients.

And thanks to constant medical advances, treatment protocols are becoming even more refined and tailored to individual needs.

Let’s Clear the Confusion - Together

Fertility treatment should empower you, not scare you. If you’re worried about risks or overwhelmed by what you’ve read online, speak with an expert who can walk you through the facts and tailor care to your health history. 

Call Annandale Fertility at 703-462-8665 to get answers and peace of mind - all in one visit

With decades of experience, our team is compassionate and patient centered. We aim to support you in your dreams and decisions, and educate you so that you have the facts you need to make informed decisions. 

We are about family, and ensuring that we get results from whatever procedure or service we perform. Your safety and well being is top priority. Ask about us, what we offer and how we can help you.